Thyrotropinoma - the case report about one of the rarest type of pituitary adenomas

Pituitary tumours are a significant diagnostic problem in clinical practice. Considering all the rarity of thyrotropic hormone secreting adenoma it is and therapeutic challenge part due to lack preoperative standards. TSH-oma, besides hyperthyroidism symptoms, might be cause other endocrine disorders, most often dysfunction tropic axes may neurological symptoms associated with sella expansion. We report case 49-year-old male patient macroadenoma, overt hyperthyroidism, secondary adrenal insufficiency hypogonadotropic hypogonadism. The diagnosis thyrotropinoma was confirmed by blood tests that revealed elevated FT3 FT4 levels together high TSH. Thyrotropin-releasing (TRH) test performed magnetic resonance imaging (MRI) presence macroadenoma. Histopathology examination cell pituitary adenoma. appropriate therapy for thyrotropin has not been elaborated reports this domain. Preoperatively prepared long-acting somatostatin analogue (Sandostatin LAR) injections reduce tumor size good effect afterwards underwent surgical transsphenoidal treatment successfully. However, specific guidelines tumors need more details.